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Yeah, runaway global warming might not happen. Plant monocultures would begin to disappear. New invasive species wouldn’t happen, though existing ones might have a better time for a bit. Major thoroughfares wouldn’t create barriers to migration. Dams might take centuries to collapse, but I think humans going extinct might have one of the biggest impacts.
The South. Just below Indiana, the middle finger of the South. And I say this as a Hoosier for much of my life.